電影《家庭主婦否定式》基于大熱舞臺劇《家庭主婦的獨白》改編。兩姐妹和她們的母親原本擁有很大分歧，但是因對家、對生活的反思，暫時擱置。 Gijsje是一位年輕、野心勃勃的控制狂。她非常渴望懷孕，也非常希望在廣告公司獲得晉升。她的姐姐Marjolein已經結婚，是三個孩子的媽媽，她剛丟了份記者的工作。不過她有了新的抱負，當一名接送孩子上下課的媽媽。她們波西米亞的母親Loes在她漂亮的房子上借了不少貸款，給自己帶來了麻煩。兩姐妹不想失去他們的家庭，開始尋找拯救的方法。只有靠Gijsje想廣告的金點子才能緩解他們的財政危機。這意味著她要與她迷人的同事Dominique探討“現代家庭主婦”這個概念。這個任務比很多人想的要復雜的多。

Two sisters and their mother are forced to set aside their differences as they reflect on the lives they are living and the homes they are running.

Gijsje is a young, ambitious control freak who is desperate to get pregnant and climb the ladder at the advertising agency where she works. Her older sister Marjolein is married with three kids and has just lost her job as a journalist. Her new ambition: to become a school run mum.

Their bohemian mother Loes has got herself into trouble by taking out too many mortgages on her beautiful home. Gijsje and Marjolein cannot bear to lose their family home and start looking for a way to save it. Only the bonus that Gijsje can earn by coming up with the golden idea for an advertising campaign can get them out of financial trouble. This means working with her attractive colleague Dominique to explore the concept of the "modern day housewife"; a task that dredges up a lot more than the women ever bargained for.

"No such thing as a housewife" is based on the popular theatre performance "The Housewife Monologues".